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- Title
THE NUCLEIC ACID CONTENT OF INFLUENZA VIRUS.
- Authors
Ada, G. L.; Perry, Beverley T.
- Abstract
Purified influenza virus (PR8 strain) has been analysed for nucleic acid content. It was found, as judged by ultraviolet absorption measurements, that the nucleic acid could be quantitatively extracted from the defatted virus with hot 10 p.c. sodium chloride. Tests for deoxypentose (indole reaction) and for deoxypentose nucleic acid phosphorus (Schmidt and Thannhauser technique) indicated that a negligible amount of deoxypentose nucleic acid was present in the extract. In four preparations in which the infectivity per haemagglutinin unit varied from 6.2 to 5.6, the average ribonucleic content of the virus was found to be 0.78 p.c. by ultraviolet absorption and 0.98 by phosphorus analyses.
- Subjects
INFLUENZA viruses; NUCLEIC acids; ANALYTICAL chemistry; BLOOD agglutination; PHYSIOLOGICAL effects of ultraviolet radiation
- Publication
Australian Journal of Experimental Biology & Medical Science, 1954, Vol 32, Issue 4, p453
- ISSN
0004-945X
- Publication type
Article
- DOI
10.1038/icb.1954.48