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- Title
The Cerebral Arterial Wall in the Development and Growth of Intracranial Aneurysms.
- Authors
Abbate, Pasquale Marco; Hasan, A. T. M. Hasibul; Venier, Alice; Vauclin, Vincent; Pizzuto, Silvia; Sgreccia, Alessandro; Maria, Federico Di; Coskun, Oguzhan; Mizutani, Katsuhiro; Rodesch, Georges; Consoli, Arturo
- Abstract
A considerable number of people harbor intracranial aneurysms (IA), which is a focal or segmental disease of the arterial wall. The pathophysiologic mechanisms of IAs formation, growth, and rupture are complex. The mechanism also differs with respect to the type of aneurysm. In broad aspects, aneurysms may be considered a disease of the vessel wall. In addition to the classic risk factors and the genetic/environmental conditions, altered structural and pathologic events along with the interaction of the surrounding environment and luminal flow dynamics contribute to the aneurysm's development and growth. In this review, we have tried to simplify the complex interaction of a multitude of events in relation to vessel wall in the formation and growth of IAs.
- Subjects
INTRACRANIAL aneurysms; DISEASE progression; ARTERIAL diseases; ANEURYSMS
- Publication
Applied Sciences (2076-3417), 2022, Vol 12, Issue 12, p5964
- ISSN
2076-3417
- Publication type
Article
- DOI
10.3390/app12125964