We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Remodeling of collagen constituting interlobular septa of subcutaneous adipose tissue following microwaves application.
- Authors
Zerbinati, Nicola; d'Este, Edoardo; Farina, Aurora; Cornaglia, Antonia I.; Jafferany, Mohammad; Golubovic, Masa; Binic, Iva; Sigova, Julia; Van Thuong, Nguyen; Tirant, Michael; Riva, Federica; Protasoni, Marina; Rauso, Raffaele; Lotti, Torello; Calligaro, Alberto
- Abstract
In this study, the application of a recently introduced device based on electromagnetic energy transfer by microwaves for fat reduction, permitted to study specifically the modifications of thick fibrous collagen interlobular septa in the subcutaneous adipose tissue, related to the formation of large clusters of adipocytes. The use of Picrosirius red staining associated with circularly polarized microscopy gave evidence of appreciable modifications of the fibrous connective tissue forming septa. Compact fibrotic bundles of collagen I forming interlobular septa appeared reduced or dissolved, in part substituted by the increase of more diffuse and finely reticular collagen III. Remodeling of fibrous collagen, which formed bridles involved in the appearance at the surface of the skin of dimpling/orange peer pattern typical of cellulite, was observed.
- Subjects
ADIPOSE tissues; COLLAGEN; ELECTROMAGNETIC waves; CONNECTIVE tissues; MICROWAVES
- Publication
Dermatologic Therapy, 2020, Vol 33, Issue 3, p1
- ISSN
1396-0296
- Publication type
Article
- DOI
10.1111/dth.13362