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The TLR2-MyD88-NOD2-RIPK2 signalling axis regulates a balanced pro-inflammatory and IL-10-mediated anti-inflammatory cytokine response to Gram-positive cell walls.
Published in:
Cellular Microbiology, 2008, v. 10, n. 10, p. 2067, doi. 10.1111/j.1462-5822.2008.01189.x
By:
- Moreira, Lilian O.;
- El Kasmi, Karim C.;
- Smith, Amber M.;
- Finkelstein, David;
- Fillon, Sophie;
- Yun-Gi Kim;
- Núñez, Gabriel;
- Tuomanen, Elaine;
- Murray, Peter J.
Publication type:
Article
Expression of circadian regulatory genes is dysregulated by increased cytokine production in mice subjected to concomitant intestinal injury and parenteral nutrition.
Published in:
PLoS ONE, 2023, v. 18, n. 8, p. 1, doi. 10.1371/journal.pone.0290385
By:
- Shearn, Colin T.;
- Anderson, Aimee L.;
- Devereaux, Michael W.;
- El Kasmi, Karim C.;
- Orlicky, David J.;
- Sokol, Ronald J.
Publication type:
Article
Immunotolerant p50/NFκB Signaling and Attenuated Hepatic IFNβ Expression Increases Neonatal Sensitivity to Endotoxemia.
Published in:
Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.02210
By:
- McKenna, Sarah;
- Burey, Taylor;
- Sandoval, Jeryl;
- Nguyen, Leanna;
- Castro, Odalis;
- Gudipati, Suma;
- Gonzalez, Jazmin;
- El Kasmi, Karim C.;
- Wright, Clyde J.
Publication type:
Article
Specific Microbiome Changes in a Mouse Model of Parenteral Nutrition Associated Liver Injury and Intestinal Inflammation.
Published in:
PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0110396
By:
- Harris, J. Kirk;
- El Kasmi, Karim C.;
- Anderson, Aimee L.;
- Devereaux, Michael W.;
- Fillon, Sophie A.;
- Robertson, Charles E.;
- Wagner, Brandie D.;
- Stevens, Mark J.;
- Pace, Norman R.;
- Sokol, Ronald J.
Publication type:
Article
Role of Arginase 1 from Myeloid Cells in Th2-Dominated Lung Inflammation.
Published in:
PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0061961
By:
- Barron, Luke;
- Smith, Amber M.;
- El Kasmi, Karim C.;
- Qualls, Joseph E.;
- Huang, Xiaozhu;
- Cheever, Allen;
- Borthwick, Lee A.;
- Wilson, Mark S.;
- Murray, Peter J.;
- Wynn, Thomas A.
Publication type:
Article
ATP Release from Vascular Endothelia Occurs Across Cx43 Hemichannels and Is Attenuated during Hypoxia.
Published in:
PLoS ONE, 2008, v. 3, n. 7, p. 1, doi. 10.1371/journal.pone.0002801
By:
- Faigle, Marion;
- Seessle, Jessica;
- Zug, Stephanie;
- El Kasmi, Karim C.;
- Eltzschig, Holger K.
Publication type:
Article
Author Correction: The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD.
Published in:
2019
By:
- Soderborg, Taylor K.;
- Clark, Sarah E.;
- Mulligan, Christopher E.;
- Janssen, Rachel C.;
- Babcock, Lyndsey;
- Ir, Diana;
- Young, Bridget;
- Kriebs, Nancy F.;
- Lemas, Dominick J.;
- Johnson, Linda K.;
- Weir, Tiffany;
- Lenz, Laurel L.;
- Frank, Daniel N.;
- Hernandez, Teri L.;
- Kuhn, Kristine A.;
- D'Alessandro, Angelo;
- Barbour, Linda A.;
- El Kasmi, Karim C.;
- Friedman, Jacob E.
Publication type:
Correction Notice
The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD.
Published in:
Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-06929-0
By:
- Soderborg, Taylor K.;
- Clark, Sarah E.;
- Mulligan, Christopher E.;
- Janssen, Rachel C.;
- Babcock, Lyndsey;
- Ir, Diana;
- Lemas, Dominick J.;
- Johnson, Linda K.;
- Weir, Tiffany;
- Lenz, Laurel L.;
- Frank, Daniel N.;
- Hernandez, Teri L.;
- Kuhn, Kristine A.;
- D’Alessandro, Angelo;
- Barbour, Linda A.;
- El Kasmi, Karim C.;
- Friedman, Jacob E.
Publication type:
Article
Interrupting tumor necrosis factor–alpha signaling prevents parenteral nutrition–associated cholestasis in mice.
Published in:
JPEN Journal of Parenteral & Enteral Nutrition, 2022, v. 46, n. 5, p. 1096, doi. 10.1002/jpen.2279
By:
- El Kasmi, Karim C.;
- Anderson, Aimee L.;
- Devereaux, Michael W.;
- Balasubramaniyan, Natarajan;
- Suchy, Frederick J.;
- Orlicky, David J.;
- Shearn, Colin T.;
- Sokol, Ronald J.
Publication type:
Article
Antifibrotic Drug Nintedanib Inhibits CSF1R to Promote IL-4-associated Tissue Repair Macrophages.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2023, v. 68, n. 4, p. 366, doi. 10.1165/rcmb.2022-0021OC
By:
- Watson, Carolin K.;
- Schloesser, Daniela;
- Fundel-Clemens, Katrin;
- Lerner, Carmen;
- Gabler, Svenja;
- Baskaran, Praveen;
- Wohnhaas, Christian T.;
- Dichtl, Stefanie;
- Huber, Heinrich J.;
- Ask, Kjetil;
- Gantner, Florian;
- Viollet, Coralie;
- Thomas, Matthew J.;
- Ramirez, Fidel;
- Murray, Peter J.;
- El Kasmi, Karim C.
Publication type:
Article
Constitutive Reprogramming of Fibroblast Mitochondrial Metabolism in Pulmonary Hypertension.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2016, v. 55, n. 1, p. 47, doi. 10.1165/rcmb.2015-0142OC
By:
- Plecitá-Hlavatá, Lydie;
- Tauber, Jan;
- Min Li;
- Hui Zhang;
- Flockton, Amanda R.;
- Pullamsetti, Soni Savai;
- Chelladurai, Prakash;
- D'Alessandro, Angelo;
- El Kasmi, Karim C.;
- Ježek, Petr;
- Stenmark, Kurt R.
Publication type:
Article
Gene-selective transcription promotes the inhibition of tissue reparative macrophages by TNF.
Published in:
Life Science Alliance, 2022, v. 5, n. 4, p. 1, doi. 10.26508/lsa.202101315
By:
- Dichtl, Stefanie;
- Sanin, David E.;
- Koss, Carolin K.;
- Willenborg, Sebastian;
- Petzold, Andreas;
- Tanzer, Maria C.;
- Dahl, Andreas;
- Kabat, Agnieszka M.;
- Lindenthal, Laura;
- Zeitler, Leonie;
- Satzinger, Sabrina;
- Strasser, Alexander;
- Mann, Matthias;
- Roers, Axel;
- Eming, Sabine A.;
- El Kasmi, Karim C.;
- Pearce, Edward J.;
- Murray, Peter J.
Publication type:
Article
IL36 is a critical upstream amplifier of neutrophilic lung inflammation in mice.
Published in:
Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-01703-3
By:
- Koss, Carolin K.;
- Wohnhaas, Christian T.;
- Baker, Jonathan R.;
- Tilp, Cornelia;
- Przibilla, Michèl;
- Lerner, Carmen;
- Frey, Silvia;
- Keck, Martina;
- Williams, Cara M. M.;
- Peter, Daniel;
- Ramanujam, Meera;
- Fine, Jay;
- Gantner, Florian;
- Thomas, Matthew;
- Barnes, Peter J.;
- Donnelly, Louise E.;
- El Kasmi, Karim C.
Publication type:
Article
Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens.
Published in:
Nature Immunology, 2008, v. 9, n. 12, p. 1399, doi. 10.1038/ni.1671
By:
- El Kasmi, Karim C;
- Qualls, Joseph E;
- Pesce, John T;
- Smith, Amber M;
- Thompson, Robert W;
- Henao-Tamayo, Marcela;
- Basaraba, Randall J;
- König, Till;
- Schleicher, Ulrike;
- Koo, Mi-Sun;
- Kaplan, Gilla;
- Fitzgerald, Katherine A;
- Tuomanen, Elaine I;
- Orme, Ian M;
- Kanneganti, Thirumala-Devi;
- Bogdan, Christian;
- Wynn, Thomas A;
- Murray, Peter J
Publication type:
Article
Microenvironmental Regulation of Macrophage Transcriptomic and Metabolomic Profiles in Pulmonary Hypertension.
Published in:
Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.640718
By:
- Li, Min;
- Riddle, Suzette;
- Kumar, Sushil;
- Poczobutt, Joanna;
- McKeon, B. Alexandre;
- Frid, Maria G.;
- Ostaff, Maureen;
- Reisz, Julie A.;
- Nemkov, Travis;
- Fini, Mehdi A.;
- Laux, Aya;
- Hu, Cheng-Jun;
- El Kasmi, Karim C.;
- D'Alessandro, Angelo;
- Brown, R. Dale;
- Zhang, Hui;
- Stenmark, Kurt R.
Publication type:
Article
Arginase-1-Expressing Macrophages Suppress Th2 Cytokine-Driven Inflammation and Fibrosis.
Published in:
PLoS Pathogens, 2009, v. 5, n. 4, p. 1, doi. 10.1371/journal.ppat.1000371
By:
- Pesce, John T.;
- Ramalingam, Thirumalai R.;
- Mentink-Kane, Margaret M.;
- Wilson, Mark S.;
- El Kasmi, Karim C.;
- Smith, Amber M.;
- Thompson, Robert W.;
- Cheever, Allen W.;
- Murray, Peter J.;
- Wynn, Thomas A.
Publication type:
Article
Phytosterols Promote Liver Injury and Kupffer Cell Activation in Parenteral Nutrition-Associated Liver Disease.
Published in:
Science Translational Medicine, 2013, v. 5, n. 206, p. 1, doi. 10.1126/scitranslmed.3006898
By:
- El Kasmi, Karim C.;
- Anderson, Aimee L.;
- Devereaux, Michael W.;
- Vue, Padade M.;
- Wujuan Zhang;
- Setchell, Kenneth D. R.;
- Karpen, Saul J.;
- Sokol, Ronald J.
Publication type:
Article
Macrophage-derived IL-1β/NF-κB signaling mediates parenteral nutrition-associated cholestasis.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03764-1
By:
- El Kasmi, Karim C.;
- Vue, Padade M.;
- Anderson, Aimee L.;
- Devereaux, Michael W.;
- Ghosh, Swati;
- Balasubramaniyan, Natarajan;
- Fillon, Sophie A.;
- Dahrenmoeller, Carola;
- Allawzi, Ayed;
- Woods, Crystal;
- McKenna, Sarah;
- Wright, Clyde J.;
- Johnson, Linda;
- D’Alessandro, Angelo;
- Reisz, Julie A.;
- Nozik-Grayck, Eva;
- Suchy, Frederick J.;
- Sokol, Ronald J.
Publication type:
Article
Targeting the adventitial microenvironment in pulmonary hypertension: A potential approach to therapy that considers epigenetic change.
Published in:
Pulmonary Circulation, 2012, v. 2, n. 1, p. 3, doi. 10.4103/2045-8932.94817
By:
- Stenmark, Kurt R.;
- Frid, Maria G.;
- Yeager, Michael;
- Min Li;
- Riddle, Suzette;
- McKinsey, Timothy;
- El Kasmi, Karim C.
Publication type:
Article
Early Life Exposure to Maternal Insulin Resistance Has Persistent Effects on Hepatic NAFLD in Juvenile Nonhuman Primates.
Published in:
Diabetes, 2014, v. 63, n. 8, p. 2702, doi. 10.2337/db14-0276
By:
- Thorn, Stephanie R.;
- Baquero, Karalee C.;
- Newsom, Sean A.;
- El Kasmi, Karim C.;
- Bergman, Bryan C.;
- Shulman, Gerald I.;
- Grove, Kevin L.;
- Friedman, Jacob E.
Publication type:
Article

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