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- Title
Salivary and serum antibodies to gliadin in the diagnosis of celiac disease.
- Authors
Ai-Bayaty, H. F.; Aldred, M. J.; Walker, D. M.; Newcombe, R. G.; Swift, G.; Smith, P. M.; Ciclitira, P. J.
- Abstract
Salivary IgA and serum IgA and IgG antibodies to crude gliadin and alphagliadin were measured in adult patients with untreated celiac disease, ulcerative colitis, Crohn's disease and normal controls. Antibody levels in saliva and serum in untreated celiac disease were significantly higher than in other groups. Alpha-gliadin antibodies appeared to be a better discriminator for serum but not for saliva, The assay of salivary IgA antibodies to gliadin offers a noninvasive test which would be particularly useful in the investigation of celiac disease and for monitoring compliance with a gluten-free diet.
- Subjects
SERUM; SALIVARY glands; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G
- Publication
Journal of Oral Pathology & Medicine, 1989, Vol 18, Issue 10, p578
- ISSN
0904-2512
- Publication type
Article
- DOI
10.1111/j.1600-0714.1989.tb01556.x