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- Title
The clinical features of radiation cataract in patients with ocular adnexal mucosa-associated lymphoid tissue lymphoma.
- Authors
Fukutsu, Kanae; Kase, Satoru; Ishijima, Kan; Kinoshita, Rumiko; Ishida, Susumu
- Abstract
<bold>Background: </bold>To examine the clinical features of radiation cataract in patients with ocular adnexal mucosa-associated lymphoid tissue (MALT) lymphoma.<bold>Methods: </bold>Twenty-one patients with 26 eyes diagnosed with ocular adnexal MALT lymphoma (26 eyes), who were treated in Hokkaido University Hospital, were retrospectively reviewed based on medical records.<bold>Results: </bold>Out of the 21 patients, 16 patients (21 eyes) received radiation therapy (RT) with a total dose of 30 Gy. All cases eventually achieved complete remission. Eight of these patients (11 eyes: 52.3%) required cataract surgery after RT. The mean age at surgery was 56.8 (40-70) years. The mean latency between RT and the indication for surgery was 43.3 months. The percentage of females was significantly higher in patients who required surgery (P < 0.01), compared with those without surgery. The eyes of patients who received bolus technique on radiation treatment developed cataract more frequently (P < 0.05). In contrast, none of the patients without RT required cataract surgery.<bold>Conclusions: </bold>Patients with ocular adnexal MALT lymphoma who underwent surgery for radiation cataract were seen more often in relatively young, female patients, and surgery was required about 3 years after RT. A long-term observation may be needed for patients after RT for a tumor. A female sex and the bolus technique may be risk factors for radiation cataract.
- Subjects
MUCOSA-associated lymphoid tissue lymphoma; CATARACT surgery; RADIOTHERAPY; LYMPHOMAS; ELECTROTHERAPEUTICS
- Publication
Radiation Oncology, 2018, Vol 13, Issue 1, pN.PAG
- ISSN
1748-717X
- Publication type
journal article
- DOI
10.1186/s13014-018-1045-7