We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Papillary adenoma of the lung: A case report and literature review.
- Authors
LI-QIAN CHEN; MAI-QING YANG; SU-MEI GAO; ZHENG-JIANG WANG; HONG-TAO XU
- Abstract
Papillary adenoma of the lung, a rare and benign tumor, is easily confused with other primary benign or malignant lung tumors and especially with lung adenocarcinoma that has a papillary growth pattern. Enhanced understanding and an accurate diagnosis of papillary adenomas of the lung are crucial for clinical treatment and prognostic assessment. A 61-year-old man who presented with an opportunistic finding in relation to a left lower lobe lung nodule during an examination was admitted to The First Hospital of China Medical University (Shenyang, China) for further treatment. Computed tomography (CT) revealed a well-circumscribed left lower lobe nodule (diameter, ~1 cm), comprising branched papillae with a fibrovascular core and no other structural components. The tumor cells appeared relatively uniform in shape and well arranged with round or oval nuclei. No nucleoli or mitotic figures were observed. Immunohistochemically, the papillary structures of the tumor cells were strongly and diffusely positive for cytokeratin (CK), CK7, Napsin-A and thyroid transcription factor 1. The Ki-67 index was ~1%. A pathological diagnosis of primary papillary adenoma of the lung was made based on these findings. A left lower-lobe wedge resection was performed and the patient's postoperative course was uneventful. Surgical resection is the preferred treatment. Papillary adenoma of the lung is very rare, and its clinical manifestations and CT images are non-specific. It is important to avoid misdiagnosing of papillary adenoma of the lung as another type of lung tumor, especially adenocarcinoma. A clear understanding of the morphological and immunohistochemical features of papillary adenomas is important for the diagnosis of this rare lung tumor.
- Subjects
LITERATURE reviews; ADENOMA; TRANSCRIPTION factors; LUNGS; LUNG tumors; BENIGN tumors; THYROID cancer
- Publication
Experimental & Therapeutic Medicine, 2024, Vol 28, Issue 3, p1
- ISSN
1792-0981
- Publication type
Article
- DOI
10.3892/etm.2024.12658