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- Title
Interferon-γ capture T cell therapy for persistent Adenoviraemia following allogeneic haematopoietic stem cell transplantation.
- Authors
Qasim, Waseem; Gilmour, Kimberly; Zhan, Hong; Derniame, Sophie; McNicol, Anne Marie; Ip, Winnie; Hiwarkar, Prashant; Veys, Paul; Gaspar, Hubert B.
- Abstract
The article presents a study concerning the use of interferon-γ capture T cell therapy in the treatment of adenoviraemia after paediatric haematopoietic stem cell transplantation (SCT). It mentions that five children were treated with intractable post-transplant adenovirus (ADV). It shows that a single infusion of 104 T cells/kg can mediate clearance of adenoviraemia, even in patients who receive on-going immunosuppression.
- Subjects
VIREMIA; INTERFERONS; T cells; HEMATOPOIETIC stem cell transplantation; ADENOVIRUSES; PEDIATRIC therapy; IMMUNOSUPPRESSION
- Publication
British Journal of Haematology, 2013, Vol 161, Issue 3, p449
- ISSN
0007-1048
- Publication type
Article
- DOI
10.1111/bjh.12251