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- Title
Clinical outcome of cardiac surgery in patients with remitted or active hepatocellular carcinoma.
- Authors
Takagi, Kazuyoshi; Arinaga, Koichi; Takaseya, Tohru; Otsuka, Hiroyuki; Shojima, Takahiro; Shintani, Yusuke; Kono, Takanori; Zaima, Yasuyuki; Kikusaki, Satoshi; Saku, Kosuke; Oryoji, Atsunobu; Tayama, Eiki
- Abstract
Purpose: Hepatocellular carcinoma (HCC) is one of the most common primary cancers worldwide. HCC has unique characteristics such as co-existing chronic liver damage and a high recurrence rate. A negative impact on the surgical outcome due to these backgrounds could be expected. We aimed to evaluate the clinical outcomes of cardiac surgery in these patients. Methods: Between January 2000 and December 2019, 16 patients with remitted cancer and 5 patients with active HCC who underwent open heart surgery were studied. The clinical data were retrospectively evaluated from hospital records. Follow-up information was collected via telephone interviews. Results: The major cause of HCC was viral hepatitis. Eighteen patients (86%) were classified as having Child–Pugh class A cirrhosis. The mean model of end-stage liver disease (MELD) score was 7.2 ± 5.2. There was no 30-day mortality. During follow-up, 11 patients died due to HCC. The 1-, 3-, and 5-year survival rates were 80.0, 42.5, and 22.3%, respectively. A univariate analysis identified a higher preoperative MELD score and lower serum cholinesterase levels as prognostic factors for long-term survival. Conclusion: We could safely perform cardiac surgery in selected patients with remitted and active HCC. The postoperative life expectancy of these patients was limited but acceptable.
- Subjects
CARDIAC surgery; TREATMENT effectiveness; HEPATOCELLULAR carcinoma; CARDIAC patients; PROGNOSIS
- Publication
Surgery Today, 2021, Vol 51, Issue 9, p1456
- ISSN
0941-1291
- Publication type
Article
- DOI
10.1007/s00595-021-02239-z