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- Title
Plasmid double locus sequence typing for IncHI2 plasmids, a subtyping scheme for the characterization of IncHI2 plasmids carrying extended-spectrum β-lactamase and quinolone resistance genes.
- Authors
García-Fernández, Aurora; Carattoli, Alessandra
- Abstract
Objectives: IncHI2 plasmids are frequently encountered in clinical enterobacterial strains associated with the dissemination of relevant antimicrobial resistance genes. These plasmids are usually >250 kb, and technical difficulties can impair plasmid DNA purification and comparison by restriction fragment length polymorphism. We analysed the available IncHI2 whole DNA plasmid sequences to devise a rapid typing scheme to categorize the members of this plasmid family into homogeneous groups.
- Subjects
PLASMIDS; BETA lactamases; QUINOLONE antibacterial agents; ANTI-infective agents; NUCLEOTIDE sequence; CYTOPLASMIC inheritance
- Publication
Journal of Antimicrobial Chemotherapy (JAC), 2010, Vol 65, Issue 6, p1155
- ISSN
0305-7453
- Publication type
Article
- DOI
10.1093/jac/dkq101