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- Title
CMOS-based implantable glucose monitoring device with improved performance and reduced invasiveness.
- Authors
Kawamura, T.; Masuda, K.; Hirai, T.; Ohta, Y.; Motoyama, M.; Takehara, H.; Noda, T.; Sasagawa, K.; Tokuda, T.; Okitsu, T.; Takeuchi, S.; Ohta, J.
- Abstract
An implantable glucose monitoring device based on a CMOS line sensor combined with a glucose-responsive fluorescent hydrogel is developed. An implantable glucose monitoring device with sufficient sensitivity and response time is realised, which is an improvement over the authors' previous proof-of-concept device. A reduction of the sensor size made the device diameter injectable with a commercially available 16-gauge syringe needle. The sensor's performance was confirmed through both in vitro and in vivo experiments.
- Subjects
COMPLEMENTARY metal oxide semiconductors; GLUCOSE; GLYCOGENOLYSIS; DETECTORS; SENSITIVITY analysis
- Publication
Electronics Letters (Wiley-Blackwell), 2015, Vol 51, Issue 10, p738
- ISSN
0013-5194
- Publication type
Article
- DOI
10.1049/el.2015.0612