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- Title
NUCLEAR COMPARTMENTALIZATION AND GENE ACTIVITY.
- Authors
Francastel, Claire; Schübeler, Dirk; Martin, David I. K.; Groudine, Mark
- Abstract
Examines a proposal that tissue-specific enhancers prevent active genes from being included in regions of transcriptionally inactive condensed chromatin that form during cell differentiation. Event that influences the regulated expression of genes during development and differentiation; Process involved in cellular differentiation; Idea behind heterochromatin.
- Subjects
TISSUES; GENES; CHROMATIN; CHROMOSOMES; CELL differentiation; MORPHOGENESIS; GENE expression; HETEROCHROMATIN
- Publication
Nature Reviews Molecular Cell Biology, 2000, Vol 1, Issue 2, p137
- ISSN
1471-0072
- Publication type
Article
- DOI
10.1038/35040083