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- Title
TRBC1 expression assessed by flow cytometry as a novel marker of clonality in cutaneous αβ T‐cell lymphomas with peripheral blood involvement.
- Authors
Martin‐Moro, Fernando; Martin‐Rubio, Isaac; Garcia‐Vela, Jose A.
- Abstract
The TRBC1 evaluation is a useful, simple, and fast flow cytometry tool for the assessment of T-cell clonality in the blood of patients suspicious of mycosis fungoides and Sézary syndrome. TRBC1 expression assessed by flow cytometry as a novel marker of clonality in cutaneous T-cell lymphomas with peripheral blood involvement The recently described monoclonal antibody JOVI-11 is directed against the C1 constant region of the TCR chain (TRBC1), and is an interesting tool for the assessment of clonality in T-cell tumours by flow cytometry (FCM).
- Subjects
CUTANEOUS T-cell lymphoma; SEZARY syndrome; T cells; FLOW cytometry; LYMPHOMAS
- Publication
British Journal of Dermatology, 2022, Vol 187, Issue 4, p623
- ISSN
0007-0963
- Publication type
Article
- DOI
10.1111/bjd.21678