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- Title
The impact of multimorbidity on resting metabolic rate in community-dwelling women over a ten-year period: A cross-sectional and longitudinal study.
- Authors
Nagel, A.; Jungert, A.; Spinneker, A.; Neuhäuser-Berthold, Monika
- Abstract
Objectives: Ageing has been associated with increasing multimorbidity. This study investigated whether the number of diseases is a predictor of resting metabolic rate (RMR) and its long-term changes in community-dwelling elderly women. Subjects and Design: Cross-sectional and longitudinal data, obtained over ten years with repeated follow-ups, from 180 women aged 60-86 years and with a BMI of 18-43 kg/m at baseline were analyzed. Measurements: RMR was measured using indirect calorimetry and body composition by bioelectrical impedance analysis. Diagnosed diseases were assessed by a questionnaire comprising 23 disease categories. Subjects with 0-2 diseases were classified as relatively healthy and with > 2 diseases as multimorbid. Results: At baseline, relatively healthy (N = 75) and multimorbid (N = 105) women did not differ in RMR. During the ten-year follow-up, the median (range) number of diseases increased from 2 (0-2) to 4 (0-8) in relatively healthy and from 5 (3-11) to 7 (3-15) in multimorbid women. In the longitudinal analyses, only women who were multimorbid at baseline showed a significant increase in RMR of 31 kJ/d per additional disease (P = 0.015), adjusted for fat-free mass, fat mass, waist circumference and age. Conclusion: Increasing multimorbidity in community-dwelling women is associated with an increase in RMR independently of body composition and age.
- Subjects
AGING; BODY composition; LONGITUDINAL method; METABOLISM; QUESTIONNAIRES; COMORBIDITY; CROSS-sectional method; WAIST circumference
- Publication
Journal of Nutrition, Health & Aging, 2017, Vol 21, Issue 7, p781
- ISSN
1279-7707
- Publication type
Article
- DOI
10.1007/s12603-016-0840-9