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- Title
Nanolayered Double Hydroxide Inhibits the Pathogenicity of Vibrio parahaemolyticus.
- Authors
Wang, Cang; Ma, Xiaoyi; Hu, Jie; Tian, Xiaopeng; Zhang, Hao; Dong, Dongxue; Fang, Zaixi; Lyu, Mingsheng; Wang, Shujun; Lu, Jing
- Abstract
Nanolayered double hydroxide (LDH) is a type of anion layered inorganic compound whose bacteriostatic properties have recently garnered much attention. Vibrio parahaemolyticus is a marine pathogen that can lead to aquaculture diseases and substantial economic losses. Therefore, our study assessed the mechanisms by which Mg/Al-LDH prevents V. parahaemolyticus infection. Our results demonstrated that Mg/Al-LDH not only inhibited V. parahaemolyticus growth but also biofilm formation. Moreover, coupling Mg/Al-LDH with hydrogen peroxide and UV irradiation further inhibited the growth and biofilm formation of V. parahaemolyticus. Additionally, Mg/Al-LDH was found to adversely affect DNA and the gelling ability of chitosan. Furthermore, exposing V. parahaemolyticus to Mg/Al-LDH led to a 54.73% and 4.3% inhibition in the expression of the toxic genes tlh and trh, respectively. Mg/Al-LDH also improved the symptoms of V. parahaemolyticus infection in Penaeus vannamei, making this a promising candidate to prevent pathogenic bacteria infection in aquaculture.
- Subjects
VIBRIO parahaemolyticus; WHITELEG shrimp; HYDROXIDES; INORGANIC compounds; PATHOGENIC bacteria; HYDROGEN peroxide
- Publication
Journal of Nanomaterials, 2021, p1
- ISSN
1687-4110
- Publication type
Article
- DOI
10.1155/2021/4945670