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- Title
Body mass index above 24 is beneficial for the 6-month survival rate in hepatocellular carcinoma patients with extrahepatic metastases.
- Authors
Yueh-Shih Chang; Jen-Seng Huang; Cho-Li Yen; Rong-Nan Chien; Cheng-Hsu Wang; Chien-Hong Lai; Tsung-Han Wu; Yii-Jeng Lan; Kun-Yun Yeh; Chang, Yueh-Shih; Huang, Jen-Seng; Yen, Cho-Li; Chien, Rong-Nan; Wang, Cheng-Hsu; Lai, Chien-Hong; Wu, Tsung-Han; Lan, Yii-Jeng; Yeh, Kun-Yun
- Abstract
<bold>Background and Objectives: </bold>To investigate the effect of overweight status on the 6-month survival rate in patients with extrahepatic hepatocellular carcinoma (HCC).<bold>Methods and Study Design: </bold>We retrospectively analyzed the records of 51 patients with hepatocellular carcinoma and extrahepatic metastases between 2007 and 2010 before treatment. The associations among overweight status (body mass index [BMI] >24 kg/m2), demographic variables, and survival outcome were analyzed by univariate and multivariate analysis.<bold>Results: </bold>BMI>24 kg/m2 was significantly associated with the 6-month survival rate (p=0.042). Gender (p=0.149), Child Pugh classification (p=0.149), Okuda staging (p=0.093), and albumin concentration >3.5 mg/dL (p=0.082) showed marginal survival benefits in univariate analysis. Multivariate analysis confirmed that BMI >24 kg/m2 was an independent prognostic factor for the 6-month survival rate (p=0.03).<bold>Conclusions: </bold>BMI >24 kg/m2 was associated with an improved 6-month survival rate in patients with extrahepatic metastatic hepatocellular carcinoma.
- Subjects
BODY mass index; SURVIVAL analysis (Biometry); LIVER cancer patients; UNIVARIATE analysis; MULTIVARIATE analysis; ADRENAL tumors; BONE marrow cancer; BONE tumors; BRAIN tumors; HEPATOCELLULAR carcinoma; LIVER tumors; LUNG tumors; LYMPH nodes; PANCREATIC tumors
- Publication
Asia Pacific Journal of Clinical Nutrition, 2017, Vol 26, Issue 4, p637
- ISSN
0964-7058
- Publication type
journal article
- DOI
10.6133/apjcn.062016.03