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- Title
Five-Year Progress of Gastric MALT Lymphoma Presenting as Gastric Outlet Obstruction.
- Authors
Soo Yeon Choi; Dae Young Cheung; Yun Jung Park; Sun Ah Suk; Jin Il Kim; Soo Heon Park
- Abstract
Background/Aims Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is the most common and best-studied extranodal marginal zone B cell lymphoma of MALT type. It is associated with Helicobacter pylori-induced chronic gastritis and features an indolent clinical course compared to the other malignant tumor. Complications such as obstruction, perforation, or bleeding are rarely observed. Methods We report a case of gastric MALT lymphoma presenting as gastric outlet obstruction (GOO). Results A 74-year-old woman visited the gastroenterology clinic for recurrent vomiting. Four years and 5 months ago she had visited for anemia. At that time, upper endoscopy revealed gastric ulcers. Histology showed chronic inflammation with H. pylori infection. Before the histology reported, she was prescribed with acid suppressant and became lost to follow-up. Two years and 8 months ago she revisited for aggravated gastric ulcers with H. pylori infection. She was prescribed for H. pylori eradication and lost again. Final histology was MALT lymphoma. At this time, gastric ulcers showed nodular base. Antrum were narrowed. Food materials stuffing the body suggested GOO. Computed tomography scan and positron emission tomography scan showed full layered encircling mass with high FDG (fluorodeoxyglucose) uptake in antrum and enlarged mesenteric lymph nodes. Laparoscopic distal gastrectomy with lymph node dissection was performed and Ann Arbor stage II MALT lymphoma with t (11;18) was diagnosed. H. pylori was negative. The patient has been followed up without recurrence or progression for more than a year. Conclusions Due to the indolent clinical course, "Watch and Wait" strategy is often employed in gastric MALT lymphoma. However, we experienced a case of gastric MALT lymphoma progressing to GOO over about 5 years.
- Subjects
MUCOSA-associated lymphoid tissue lymphoma; GASTRIC outlet obstruction; POSITRON emission tomography; LYMPHADENECTOMY; HELICOBACTER pylori; LYMPHOID tissue
- Publication
Gut & Liver, 2019, Vol 13, Issue 6(suppl. 1), p148
- ISSN
1976-2283
- Publication type
Article