We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Role of dyslipidemia in early vascular aging syndrome.
- Authors
KILIÇ, Alparslan; BAYDAR, Onur; ELÇİK, Deniz; APAYDIN, Ziya; CAN, Mehmet Mustafa
- Abstract
Background/aim: Arterial stiffness, known as a predictor of early vascular aging, was defined as the main determinant of cardiovascular mortality and morbidity. However, the relationship between lipid profile and increased arterial stiffness is not clear. The aim of this study is to investigate the relationship between lipid profiles and increased arterial stiffness in patients with early vascular aging syndrome. Materials and methods: A total of 1582 participants --504 (31.8%) of were male and the mean age was 52.8 ±14.2 years-- were included in the study. Patients who applied to the hospital for various reasons and who had undergone 24-h blood pressure Holter monitoring were included in this study. Patients were divided into four groups according to pulse wave velocity (PWV) quartiles (Q1 (<6.3), Q2 (6.3-7.4), Q3 (7.5-8.8), Q4 (>8.8)). Results: We found that in the highest PWV group, patients had higher systolic blood pressure (SBP), diastolic blood pressure (DBP), glucose, blood urea nitrogen (BUN), creatinine, urinary albumin excretion (UAE), uric acid(UA), total cholesterol (TC), low-density lipoprotein (LDL-C), triglycerid (TG), and non- high-density lipoprotein (HDL-C) levels. Additionally, diabetes mellitus (dm), age, non-HDL-C, and TG/ HDL-C levels were detected as independent risk factors of increased PWV in ordinal logistic regression analysis. Conclusion: Our study demonstrates that lipid parameters are strongly correlated with increased PWV value and early vascular aging. In daily clinical practice, TG\HDL-C ratio, known as atherogenic index, might be used routinely for predicted of early vascular aging and subclinical atherosclerosis.
- Subjects
AGE factors in well-being; SYSTOLIC blood pressure; HIGH density lipoproteins; HYPERTENSION; BLOOD urea nitrogen; ARTERIAL diseases; LOGISTIC regression analysis
- Publication
Turkish Journal of Medical Sciences, 2021, Vol 51, Issue 2, p727
- ISSN
1300-0144
- Publication type
Article
- DOI
10.3906/sag-2008-165