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- Title
Utility of Real Time 3D Echocardiography for the Assessment of Left Ventricular Mass in Patients with Hypertrophic Cardiomyopathy: Comparison with Cardiac Magnetic Resonance.
- Authors
Avegliano, Gustavo P.; Costabel, Juan P.; Asch, Federico M.; Sciancalepore, Agustina; Kuschnir, Paola; Huguet, Marina; Tobon‐Gomez, Catalina; Frangi, Alejandro F.; Ronderos, Ricardo
- Abstract
Introduction and objectives Patients with hypertrophic cardiomyopathy ( HCM) have irregular ventricular shapes with small and sometimes obliterated cavities at end-systole that affect the quantification of left ventricular mass ( LVM) by conventional methods, such as M-mode or two-dimensional echocardiography. The goal of this study was to validate the use of real time three-dimensional echocardiography ( RT3 DE) to quantify LVM using cardiac magnetic resonance imaging ( CMR) as a reference, in a large population of patients with different types of HCM. Methods Forty-eight consecutive patients with HCM had a complete transthoracic examination and CMR performed within 7 days. LVM was calculated by M-mode and RT3 DE and compared to CMR that served as gold standard. Results Left ventricular mass calculated by RT3 DE was 195 ± 41 g and 187 ± 49 g by CMR. The correlation between the two methods was moderate, with a Lin index of 0.63 and good linear correlation (r = 0.63, P < 0.0001). The correlation was high when RT3 DE was of high or adequate image quality. The correlation between LVM by M-mode and CMR was poor. Conclusion Three-dimensional echocardiography is an accurate method for the quantification of LVM in patients with different subtypes of HCM that is in better agreement with CMR reference values than M-mode measurements.
- Subjects
HYPERTROPHIC cardiomyopathy; HEART radiography; CHI-squared test; CONFIDENCE intervals; STATISTICAL correlation; ECHOCARDIOGRAPHY; FISHER exact test; LEFT heart ventricle; LONGITUDINAL method; MAGNETIC resonance imaging; PROBABILITY theory; RESEARCH evaluation; T-test (Statistics); INTER-observer reliability; REPEATED measures design; DATA analysis software; DESCRIPTIVE statistics; ODDS ratio; DISEASE complications
- Publication
Echocardiography, 2016, Vol 33, Issue 3, p431
- ISSN
0742-2822
- Publication type
Article
- DOI
10.1111/echo.13096