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- Title
The Use of Sorafenib in the Thyroid Cancer.
- Authors
Zygulska, Aneta L.; Krzemieniecki, Krzysztof; Sowa-Staszczak, Anna
- Abstract
There are not effective therapies for metastatic unresectable, non-RAI-avid thyroid carcinomas. Fortunately, thyroid carcinomas represent a promising paradigm for targeted therapy due to the presence of activing mutations of genes coding the kinase tyrosines which are involved in all functions of cancer cells (such as: growth or invasion). In this paper an efficacy and toxicity of sorafenib, one of the multi-kinase inhibitors in thyroid carcinomas treatment is presented.
- Subjects
THYROID cancer; SORAFENIB; METASTASIS; GENETIC mutation; GENES; KINASE inhibitors; THYROID cancer treatment
- Publication
European Endocrinology, 2013, Vol 9, Issue 1, p28
- ISSN
1758-3772
- Publication type
Article
- DOI
10.17925/EE.2013.09.01.28