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- Title
Associations Between Medical History, Cognition, and Behavior in Youth With Down Syndrome: A Report From the Down Syndrome Cognition Project.
- Authors
Rosser, Tracie C.; Edgin, Jamie O.; Capone, George T.; Hamilton, Debra R.; Allen, Emily G.; Dooley, Kenneth J.; Anand, Payal; Strang, John F.; Armour, A. Chelsea; Frank-Crawford, Michelle A.; Channell, Marie Moore; Pierpont, Elizabeth I.; Feingold, Eleanor; Maslen, Cheryl L.; Reeves, Roger H.; Sherman, Stephanie L.
- Abstract
The cause of the high degree of variability in cognition and behavior among individuals with Down syndrome (DS) is unknown. We hypothesized that birth defects requiring surgery in the first years of life (congenital heart defects and gastrointestinal defects) might affect an individual's level of function. We used data from the first 234 individuals, age 6-25 years, enrolled in the Down Syndrome Cognition Project (DSCP) to test this hypothesis. Data were drawn from medical records, parent interviews, and a cognitive and behavior assessment battery. Results did not support our hypothesis. That is, we found no evidence that either birth defect was associated with poorer outcomes, adjusting for gender, race/ethnicity, and socioeconomic status. Implications for study design and measurement are discussed.
- Subjects
DOWN syndrome; DISEASES in youths; HISTORY of medicine; HUMAN abnormalities; SOCIAL status
- Publication
American Journal on Intellectual & Developmental Disabilities, 2018, Vol 123, Issue 6, p514
- ISSN
1944-7515
- Publication type
journal article
- DOI
10.1352/1944-7558-123.6.514