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- Title
Effects and safety of use off label of the topiramate on weight loss.
- Authors
Machado de Carvalho, Ana Flãvia; Madeira Marinho, Fernando Antonio; da Silva, Francisco Laurindo
- Abstract
Objective: to conduct a survey in the rational and international literature on the efficacy and safety of Topiramate In o -label use in weight loss. Method: This is an integrative review, in which the search for data was carried out in PUBMED, Embase and Cochrane, between the years 2016 to 2021,10 researches were selected. Results: Topiramate can be a safe and effective therapeutic tool in the treatment of obesity, providing a reduction in body mass index, favoring glycemic control and blood pressure, both in adults and adolescents. Adverse effects associated with treatment mainly included dysgeusia, paresthesia and dry mouth. Conclusion: Topiramate used alone or in combination with metformin, phentermine, bupropion-naltrexone and Ispagula showed beneficiai effects on weight loss.
- Subjects
TOPIRAMATE; WEIGHT loss; BLOOD pressure; METFORMIN; PARESTHESIA
- Publication
Saúde Coletiva, 2021, Vol 11, Issue 68, p7550
- ISSN
1806-3365
- Publication type
Article
- DOI
10.36489/saudecoletiva.2021v11i68p7545-7554