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- Title
Cardiovascular Complications in Diabetic Patients Undergoing Regular Hemodialysis: A 5-Year Observational Study.
- Authors
Al-Thani, Hassan; Shabana, Adel; Hussein, Ahmed; Sadek, Ahmed; Sharaf, Ahmed; Koshy, Valsa; El-Menyar, Ayman
- Abstract
We aimed to study the vascular outcomes in hemodialysis (HD) patients based on their diabetic status. A cohort observational study was conducted among patients undergoing regular HD with a 5-year follow-up. Of the 252 consecutive HD patients, 60% were diabetic. Compared with nondiabetics, diabetics were 11 years older, 4 years lesser on HD, and more likely to have prior cerebrovascular and coronary artery disease (CAD). Overall 5-year follow-up showed that diabetic patients had higher rates of HD vascular accesses (57% vs 41%, P = .01), CAD (64% vs 33%, P = .001), major amputations (8.6% vs 0%, P = .003), and mortality (66% vs 23%, P = .001). On multivariate analysis, independent predictors of mortality included number of vascular accesses in nondiabetics and HD duration, CAD, and peripheral artery disease in diabetic patients. Diabetes mellitus is associated with a significant vascular burden and mortality among HD patients. Moreover, our finding highlights the vascular impact of renal failure and HD.
- Subjects
QATAR; TREATMENT of chronic kidney failure; DIABETES complications; CARDIOVASCULAR diseases; CONFIDENCE intervals; STATISTICAL correlation; HEMODIALYSIS; LONGITUDINAL method; EVALUATION of medical care; MORTALITY; MULTIVARIATE analysis; SCIENTIFIC observation; T-test (Statistics); DATA analysis software; DESCRIPTIVE statistics; ODDS ratio; MANN Whitney U Test
- Publication
Angiology, 2015, Vol 66, Issue 3, p225
- ISSN
0003-3197
- Publication type
Article
- DOI
10.1177/0003319714523672