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- Title
A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes.
- Authors
Ishii, Naoaki; Fujii, Michihiko; Hartman, Philip S.; Tsuda, Michio; Yasuda, Kayo; Senoo-Matsuda, Nanami; Yanase, Sumino; Ayusawa, Dai; Suzuki, Kenshi
- Abstract
Presents research which showed that the mev-1 gene of Caenorhabditis elegans governs the rate of aging by modulating the cellular response to oxidative stress. Etiology of oxidative damage in cellular and organismal aging; Lifespan of the mev-1 mutant; Encoding by mev-1; Genetic traits of mev-1 animals; Aging and superoxide levels.
- Subjects
CAENORHABDITIS elegans; CELLULAR aging; SUPEROXIDES; CELLULAR control mechanisms; CYTOGENETICS
- Publication
Nature, 1998, Vol 394, Issue 6694, p694
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/29331