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- Title
Inhibitory effects of verapamil and diltiazem on simvastatin metabolism in human liver microsomes.
- Authors
Yeo, Karen Rowland; Yeo, Wilfred W.
- Abstract
Studies the effects of verapamil and diltiazem on the metabolism of the HMA-coenzyme a reductase inhibitor simvastatin in human liver chromosomes. Comparison of inhibitory potencies; Inactivation parameters; Drug dosage and administration; Pharmacokinetics.
- Subjects
STATINS (Cardiovascular agents); VERAPAMIL
- Publication
British Journal of Clinical Pharmacology, 2001, Vol 51, Issue 5, p461
- ISSN
0306-5251
- Publication type
Article
- DOI
10.1046/j.1365-2125.2001.01386.x