We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Effect of Fluoride-Containing Toothpastes on Enamel Demineralization and Streptococcus mutans Biofilm Architecture.
- Authors
Fernández, Constanza E.; Fontana, Margherita; Samarian, Derek; Cury, Jaime a.; Rickard, alexander H.; González-Cabezas, Carlos
- Abstract
This study aimed to explore the effect of fluoridated toothpastes on biofilm architecture and enamel demineralization in an in vitro biofilm model. Streptococcus mutans was grown on enamel and treated with slurries of commercial toothpastes, containing SnF2 or NaF. Water and chlorhexidine were used as negative and positive controls, respectively. The developed biofilms were imaged and enamel demineralization was measured. SnF2 and NaF toothpaste treatments significantly reduced enamel demineralization, but SnF2 toothpaste was more effective. Only SnF2 toothpaste and chlorhexidine treatments caused reductions on biofilm mass and thickness. In conclusion, this biofilm model was able to differentiate the effects of the SnF2 and NaF toothpastes on biofilm architecture and enamel demineralization.
- Subjects
TOOTHPASTE; DENTAL enamel; TOOTH demineralization; TOOTH erosion; TREATMENT of dental caries; STREPTOCOCCUS mutans; BIOFILMS; THERAPEUTICS; ANIMAL experimentation; CATTLE; CHLORHEXIDINE; DENTIFRICES; DOSE-effect relationship in pharmacology; FLUORIDES; HYDROGEN-ion concentration; MICROSCOPY; SALIVA; SODIUM compounds; THREE-dimensional imaging; IN vitro studies; PHARMACODYNAMICS; PREVENTION
- Publication
Caries Research, 2016, Vol 50, Issue 2, p151
- ISSN
0008-6568
- Publication type
journal article
- DOI
10.1159/000444888