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- Title
Statins Do Not Decrease Small, Dense Low-Density Lipoprotein.
- Authors
Cheol Ung Choi; Hong Seog Seo; Eun Mi Lee; Seung Yong Shin; Un-Jung Choi; Jin Oh Na; Lim, Hong Euy; Jin Won Kim; Eung Ju Kim; Seung-Woon Rha; Park, Chang Gyu; Dong Joo Oh
- Abstract
The article discusses a study on the effect of statins on low-density-lipoprotein (LDL) subfractions. Small, dense LDL density was measured in 612 patients using density-gradient ultracentrifugation. It was found that total cholesterol, LDL cholesterol, LDL cholesterol/apolipoprotein B ratio, and apolipoprotein B were significantly lower in the statin group. The study suggested that statin therapy does not decrease the proportion of small, dense LDL among total LDL particles, but increases it.
- Subjects
STATINS (Cardiovascular agents); LOW density lipoproteins; ULTRACENTRIFUGATION; CHOLESTEROL; APOLIPOPROTEIN B
- Publication
Texas Heart Institute Journal, 2010, Vol 37, Issue 4, p421
- ISSN
1526-6702
- Publication type
Article