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- Title
Pseudocystic dermatofibrosarcoma protuberans: report of two cases and demonstration of COL1A1-PDGFB rearrangement.
- Authors
Shvartsbeyn, Marianna; Lazar, Alexander J. F.; Lopez-Terrada, Dolores; Meehan, Shane A.
- Abstract
We report two unique cases of dermatofibrosarcoma protuberans (DFSP) that included a pseudocystic component. Molecular analysis of one of the cases showed a characteristic COL1A1-PDGFB rearrangement in both the main tumor and also in the cells lining the pseudocystic portion of the tumor, confirming the diagnosis and indicating that the lining represented a component of the proliferation. It is important to raise awareness of this rare variant within the varied spectrum of DFSP. Shvartsbeyn M, Lazar AJF, Lopez-Terrada D, Meehan SA. Pseudocystic dermatofibrosarcoma protuberans: report of two cases and demonstration of COL1A1-PDGFB rearrangement.
- Subjects
FIBROSARCOMA; TUMORS; CELL proliferation; DIAGNOSIS; CYTOPLASM
- Publication
Journal of Cutaneous Pathology, 2012, Vol 39, Issue 3, p356
- ISSN
0303-6987
- Publication type
Article
- DOI
10.1111/j.1600-0560.2011.01852.x