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Mesenchymal soluble factors confer imatinib drug resistance in chronic myelogenous leukemia cells.
- Published in:
- 2021
- By:
- Publication type:
- journal article
Differential Effects of Selective Inhibitors Targeting the PI3K/AKT/mTOR Pathway in Acute Lymphoblastic Leukemia.
- Published in:
- PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0080070
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- Publication type:
- Article
Sulindac Sulfide Reverses Aberrant Self-Renewal of Progenitor Cells Induced by the AML-Associated Fusion Proteins PML/RARα and PLZF/RARα.
- Published in:
- PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0022540
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- Publication type:
- Article
Reciprocal t(9;22) ABL/BCR Fusion Proteins: Leukemogenic Potential and Effects on B Cell Commitment.
- Published in:
- PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007661
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- Publication type:
- Article
Activation of signaling pathways in models of t(6;9)-acute myeloid leukemia.
- Published in:
- 2022
- By:
- Publication type:
- journal article
Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1T315I and BCR-ABL1T315I-E255K.
- Published in:
- Annals of Hematology, 2021, v. 100, n. 8, p. 2023, doi. 10.1007/s00277-020-04357-z
- By:
- Publication type:
- Article
Platinum (IV)-fatty acid conjugates overcome inherently and acquired Cisplatin resistant cancer cell lines: an in-vitro study.
- Published in:
- 2016
- By:
- Publication type:
- journal article
<sup>89</sup>Zr-labelled Obinutuzumab: a potential immuno-PET radiopharmaceutical.
- Published in:
- Journal of Radioanalytical & Nuclear Chemistry, 2022, v. 331, n. 12, p. 5507, doi. 10.1007/s10967-022-08614-5
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- Publication type:
- Article
Leukemia-associated translocation products able to activate RAS modify PML and render cells sensitive to arsenic-induced apoptosis.
- Published in:
- Oncogene, 2003, v. 22, n. 44, p. 6900, doi. 10.1038/sj.onc.1206747
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- Publication type:
- Article
Oleylamine-carbonyl-valinol inhibits auto-phosphorylation activity of native and T315I mutated Bcr-Abl, and exhibits selectivity towards oncogenic Bcr-Abl in SupB15 ALL cell lines.
- Published in:
- Molecular Biology Reports, 2013, v. 40, n. 3, p. 2205, doi. 10.1007/s11033-012-2282-8
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- Publication type:
- Article
The acute promyelocytic leukaemia specific PML and PLZF proteins localize to adjacent and functionally distinct nuclear bodies.
- Published in:
- Oncogene, 1998, v. 16, n. 15, p. 1945, doi. 10.1038/sj.onc.1201722
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- Publication type:
- Article
Clinical trial of valproic acid and all‐trans retinoic acid in patients with poor‐risk acute myeloid leukemia.
- Published in:
- Cancer (0008543X), 2005, v. 104, n. 12, p. 2717, doi. 10.1002/cncr.21589
- By:
- Publication type:
- Article
Targeting of the N-terminal coiled coil oligomerization interface by a helix-2 peptide inhibits unmutated and imatinib-resistant BCR/ABL.
- Published in:
- International Journal of Cancer, 2008, v. 122, n. 12, p. 2744, doi. 10.1002/ijc.23467
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- Publication type:
- Article
The Functional Interplay Between the t(9;22)-Associated Fusion Proteins BCR/ABL and ABL/BCR in Philadelphia Chromosome-Positive Acute Lymphatic Leukemia.
- Published in:
- PLoS Genetics, 2015, v. 11, n. 4, p. 1, doi. 10.1371/journal.pgen.1005144
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- Publication type:
- Article
Understanding a high-risk acute myeloid leukemia by analyzing the interactome of its major driver mutation.
- Published in:
- PLoS Genetics, 2022, v. 18, n. 10, p. 1, doi. 10.1371/journal.pgen.1010463
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- Publication type:
- Article
Folinic acid antagonizes methotrexate-induced differentiation of monocyte progenitors.
- Published in:
- Rheumatology International, 2002, v. 22, n. 2, p. 60, doi. 10.1007/s00296-002-0188-9
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- Publication type:
- Article
Overcoming Bcr-Abl T315I mutation by combination of GNF-2 and ATP competitors in an Abl-independent mechanism.
- Published in:
- BMC Cancer, 2012, v. 12, n. 1, p. 1, doi. 10.1186/1471-2407-12-563
- By:
- Publication type:
- Article
Overcoming Bcr-Abl T315I mutation by combination of GNF-2 and ATP competitors in an Abl-independent mechanism.
- Published in:
- 2012
- By:
- Publication type:
- journal article
Allosteric inhibition enhances the efficacy of ABL kinase inhibitors to target unmutated BCR-ABL and BCR-ABL-T315I.
- Published in:
- BMC Cancer, 2012, v. 12, n. 1, p. 411, doi. 10.1186/1471-2407-12-411
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- Publication type:
- Article
The effect of the dual Src/Abl kinase inhibitor AZD0530 on Philadelphia positive leukaemia cell lines.
- Published in:
- 2009
- By:
- Publication type:
- journal article
The effect of the dual Src/Abl kinase inhibitor AZD0530 on Philadelphia positive leukaemia cell lines.
- Published in:
- BMC Cancer, 2009, v. 9, p. 1, doi. 10.1186/1471-2407-9-53
- By:
- Publication type:
- Article
BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility.
- Published in:
- BMC Cancer, 2006, v. 6, p. 262, doi. 10.1186/1471-2407-6-262
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- Publication type:
- Article