We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Towards multi-phase postmortem CT angiography in children: a study on a porcine model.
- Authors
Meyrignac, O.; Rousseau, H.; Mokrane, F. Z.; Crubézy, É.; Telmon, N.; Dedouit, F.; Dercle, L.
- Abstract
Purpose: Multi-phase postmortem computed tomography angiography (MPMCTA) is a growing technique, which is standardized for adults. Application of this protocol for a children population is not so well defined. Our study aims to adapt the adult’s protocol to children, using a porcine model.Material and methods: Three groups of 18 pigs were studied, with a weight distribution between 4 and 48 kg. Different pump devices were used. Pigs of group I were studied using the Virtangio® machine, whereas pigs of groups II and III were studied using used the Medrad® machine. Study of vascular opacification was possible using a semi-quantitative method based on 26 arterial and 26 venous segments that were distributed over the entire body from the cephalic extremity to the posterior pawns.Results: While thoracic, abdominal, and pelvic vascular opacification were complete for each individual pig in a group, group III showed better vascular opacification for the cephalic extremity. This was also true for anterior and posterior pawns vascular opacification. Spearman correlation tests showed a significant relationship between anthropometric characteristics of pigs, injection parameters, and percentage of opacified segments. A higher percentage of opacification was obtained for individuals of lower weights, with comparatively lower quantities of contrast agent injected.Conclusion: Postmortem computed tomography angiography (PMCTA) was possible for all the individuals, particularly for small weights (4 kg) using the Medrad® machine. However, further studies are needed to better understand the procedure.
- Subjects
AUTOPSY; COMPUTED tomography; ANGIOGRAPHY; ANIMAL models in research; FORENSIC anthropology
- Publication
International Journal of Legal Medicine, 2018, Vol 132, Issue 5, p1391
- ISSN
0937-9827
- Publication type
Article
- DOI
10.1007/s00414-018-1783-y