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Aggregating Data for Computational Toxicology Applications: The U.S. Environmental Protection Agency (EPA) Aggregated Computational Toxicology Resource (ACToR) System.
- Published in:
- International Journal of Molecular Sciences, 2012, v. 13, n. 2, p. 1805, doi. 10.3390/ijms13021805
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- Publication type:
- Article
Using Zebrafish to Screen Developmental Toxicity of Per- and Polyfluoroalkyl Substances (PFAS).
- Published in:
- Toxics, 2024, v. 12, n. 7, p. 501, doi. 10.3390/toxics12070501
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- Publication type:
- Article
A Comparison of In Vitro Points of Departure with Human Blood Levels for Per- and Polyfluoroalkyl Substances (PFAS).
- Published in:
- Toxics, 2024, v. 12, n. 4, p. 271, doi. 10.3390/toxics12040271
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- Publication type:
- Article
A Machine Learning Model to Estimate Toxicokinetic Half-Lives of Per- and Polyfluoro-Alkyl Substances (PFAS) in Multiple Species.
- Published in:
- Toxics, 2023, v. 11, n. 2, p. 98, doi. 10.3390/toxics11020098
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- Publication type:
- Article
Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms.
- Published in:
- Nature Biotechnology, 2014, v. 32, n. 6, p. 583, doi. 10.1038/nbt.2914
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- Publication type:
- Article
Evaluation of 309 Environmental Chemicals Using a Mouse Embryonic Stem Cell Adherent Cell Differentiation and Cytotoxicity Assay.
- Published in:
- PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0018540
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- Publication type:
- Article
Using Nuclear Receptor Activity to Stratify Hepatocarcinogens.
- Published in:
- PLoS ONE, 2011, v. 6, n. 2, p. 1, doi. 10.1371/journal.pone.0014584
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- Publication type:
- Article
Comment on "On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens".
- Published in:
- 2017
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- Publication type:
- Letter to the Editor
The Next Generation of Risk Assessment Multi-Year Study--Highlights of Findings, Applications to Risk Assessment, and Future Directions.
- Published in:
- Environmental Health Perspectives, 2016, v. 124, n. 11, p. 1671, doi. 10.1289/EHP233
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- Publication type:
- Article
Systems Toxicology of Male Reproductive Development: Profiling 774 Chemicals for Molecular Targets and Adverse Outcomes.
- Published in:
- Environmental Health Perspectives, 2016, v. 124, n. 7, p. 1050, doi. 10.1289/ehp.1510385
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- Publication type:
- Article
Using ToxCast™ Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of Departure.
- Published in:
- Environmental Health Perspectives, 2016, v. 124, n. 7, p. 910, doi. 10.1289/ehp.1409029
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- Publication type:
- Article
Computational Exposure Science: An Emerging Discipline to Support 21st-Century Risk Assessment.
- Published in:
- Environmental Health Perspectives, 2016, v. 124, n. 6, p. 697, doi. 10.1289/ehp.1509748
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- Publication type:
- Article
Chemical Safety Assessment Using Read-Across: Assessing the Use of Novel Testing Methods to Strengthen the Evidence Base for Decision Making.
- Published in:
- Environmental Health Perspectives, 2015, v. 123, n. 12, p. 1232, doi. 10.1289/ehp.1409342
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- Publication type:
- Article
Using in Vitro High Throughput Screening Assays to Identify Potential Endocrine-Disrupting Chemicals.
- Published in:
- 2013
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- Publication type:
- Journal Article
Supplemental Material. Using in Vitro High-Throughput Screening Assays to Identify Potential Endocrine Disrupting Chemicals.
- Published in:
- Environmental Health Perspectives, 2013, v. 121, n. 1, p. 1, doi. 10.1289/ehp.1205065
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- Publication type:
- Article
Environmental Impact on Vascular Development Predicted by High-Throughput Screening.
- Published in:
- 2011
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- Publication type:
- Journal Article
Environmental Impact on Vascular Development Predicted by High-Throughput Screening.
- Published in:
- Environmental Health Perspectives, 2011, v. 119, n. 11, p. 1596, doi. 10.1289/ehp.1103412
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- Publication type:
- Article
Chemical Genomics Profiling of Environmental Chemical Modulation of Human Nuclear Receptors.
- Published in:
- Environmental Health Perspectives, 2011, v. 119, n. 8, p. 1142, doi. 10.1289/ehp.1002952
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- Publication type:
- Article
Endocrine Profiling and Prioritization of Environmental Chemicals Using ToxCast Data.
- Published in:
- Environmental Health Perspectives, 2010, v. 118, n. 12, p. 1714, doi. 10.1289/ehp.1002180
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- Publication type:
- Article
In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project.
- Published in:
- Environmental Health Perspectives, 2010, v. 118, n. 4, p. 485, doi. 10.1289/ehp.0901392
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- Publication type:
- Article
Profiling Chemicals Based on Chronic Toxicity Results from the U.S. EPA ToxRef Database.
- Published in:
- Environmental Health Perspectives, 2009, v. 117, n. 3, p. 392, doi. 10.1289/ehp.0800074
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- Publication type:
- Article
Exploring non-linear distance metrics in the structure-activity space: QSAR models for human estrogen receptor.
- Published in:
- Journal of Cheminformatics, 2018, v. 10, n. 1, p. 1, doi. 10.1186/s13321-018-0300-0
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- Publication type:
- Article
OPERA models for predicting physicochemical properties and environmental fate endpoints.
- Published in:
- Journal of Cheminformatics, 2018, v. 10, n. 1, p. 0, doi. 10.1186/s13321-018-0263-1
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- Publication type:
- Article
Characterizing cleft palate toxicants using ToxCast data, chemical structure, and the biomedical literature.
- Published in:
- Birth Defects Research, 2020, v. 112, n. 1, p. 19, doi. 10.1002/bdr2.1581
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- Publication type:
- Article
Pharmacogenetic Issues in Thorough QT Trials.
- Published in:
- Molecular Diagnosis & Therapy, 2006, v. 10, n. 3, p. 153, doi. 10.1007/BF03256454
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- Publication type:
- Article
Profiling the Reproductive Toxicity of Chemicals from Multigeneration Studies in the Toxicity Reference Database.
- Published in:
- Toxicological Sciences, 2009, v. 110, n. 1, p. 181, doi. 10.1093/toxsci/kfp080
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- Publication type:
- Article
Workflow for Defining Reference Chemicals for Assessing Performance of In Vitro Assays.
- Published in:
- Altex, 2019, v. 36, n. 2, p. 261, doi. 10.14573/altex.1809281
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- Publication type:
- Article
Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway.
- Published in:
- Scientific Reports, 2014, p. 1, doi. 10.1038/srep05664
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- Publication type:
- Article
Empirical models for anatomical and physiological changes in a human mother and fetus during pregnancy and gestation.
- Published in:
- PLoS ONE, 2019, v. 14, n. 5, p. 1, doi. 10.1371/journal.pone.0215906
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- Publication type:
- Article
Uncertainty quantification in ToxCast high throughput screening.
- Published in:
- PLoS ONE, 2018, v. 13, n. 7, p. 1, doi. 10.1371/journal.pone.0196963
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- Publication type:
- Article
High-Throughput Transcriptomics Platform for Screening Environmental Chemicals.
- Published in:
- Toxicological Sciences, 2021, v. 181, n. 1, p. 68, doi. 10.1093/toxsci/kfab009
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- Publication type:
- Article
Corrigendum to: "Profiling the ToxCast Library With a Pluripotent Human (H9) Stem Cell Line-Based Biomarker Assay for Developmental Toxicity".
- Published in:
- Toxicological Sciences, 2020, v. 177, n. 1, p. 301, doi. 10.1093/toxsci/kfaa064
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- Publication type:
- Article
Profiling the ToxCast Library With a Pluripotent Human (H9) Stem Cell Line-Based Biomarker Assay for Developmental Toxicity.
- Published in:
- Toxicological Sciences, 2020, v. 174, n. 2, p. 189, doi. 10.1093/toxsci/kfaa014
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- Publication type:
- Article
Next Generation Blueprint of Computational Toxicology at the U.S. Environmental Protection Agency.
- Published in:
- Toxicological Sciences, 2019, v. 169, n. 2, p. 317, doi. 10.1093/toxsci/kfz058
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- Publication type:
- Article
Erratum to “High-Throughput H295R Steroidogenesis Assay: Utility as an Alternative and a Statistical Approach to Characterize Effects on Steroidogenesis”.
- Published in:
- 2018
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- Publication type:
- Correction Notice
High-Throughput H295R Steroidogenesis Assay: Utility as an Alternative and a Statistical Approach to Characterize Effects on Steroidogenesis.
- Published in:
- Toxicological Sciences, 2018, v. 162, n. 2, p. 509, doi. 10.1093/toxsci/kfx274
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- Publication type:
- Article
Genetic Targets of Acute Toluene Inhalation in Drosophila melanogaster.
- Published in:
- Toxicological Sciences, 2017, v. 156, n. 1, p. 230, doi. 10.1093/toxsci/kfw243
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- Publication type:
- Article
Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries.
- Published in:
- Toxicological Sciences, 2016, v. 151, n. 1, p. 160, doi. 10.1093/toxsci/kfw034
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- Publication type:
- Article
Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor.
- Published in:
- Toxicological Sciences, 2015, v. 148, n. 1, p. 137, doi. 10.1093/toxsci/kfv168
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- Publication type:
- Article
Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing.
- Published in:
- Toxicological Sciences, 2015, v. 148, n. 1, p. 121, doi. 10.1093/toxsci/kfv171
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- Publication type:
- Article
EADB: An Estrogenic Activity Database for Assessing Potential Endocrine Activity.
- Published in:
- Toxicological Sciences, 2013, v. 135, n. 2, p. 277, doi. 10.1093/toxsci/kft164
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- Publication type:
- Article
Relative Impact of Incorporating Pharmacokinetics on Predicting In Vivo Hazard and Mode of Action from High-Throughput In Vitro Toxicity Assays.
- Published in:
- Toxicological Sciences, 2013, v. 132, n. 2, p. 327, doi. 10.1093/toxsci/kft012
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- Publication type:
- Article
In Vitro Perturbations of Targets in Cancer Hallmark Processes Predict Rodent Chemical Carcinogenesis.
- Published in:
- Toxicological Sciences, 2013, v. 131, n. 1, p. 40, doi. 10.1093/toxsci/kfs285
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- Publication type:
- Article
Incorporating Biological, Chemical, and Toxicological Knowledge Into Predictive Models of Toxicity.
- Published in:
- Toxicological Sciences, 2012, v. 130, n. 2, p. 440, doi. 10.1093/toxsci/kfs281
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- Publication type:
- Article
Response to “Accurate Risk-Based Chemical Screening Relies on Robust Exposure Estimates”.
- Published in:
- Toxicological Sciences, 2012, v. 128, n. 1, p. 297, doi. 10.1093/toxsci/kfs144
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- Publication type:
- Article
Integration of Dosimetry, Exposure, and High-Throughput Screening Data in Chemical Toxicity Assessment.
- Published in:
- Toxicological Sciences, 2012, v. 125, n. 1, p. 157, doi. 10.1093/toxsci/kfr254
- By:
- Publication type:
- Article
Predictive Models of Prenatal Developmental Toxicity from ToxCast High-Throughput Screening Data.
- Published in:
- Toxicological Sciences, 2011, v. 124, n. 1, p. 109, doi. 10.1093/toxsci/kfr220
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- Publication type:
- Article
A Novel Framework for Predicting In Vivo Toxicities from In Vitro Data Using Optimal Methods for Dense and Sparse Matrix Reordering and Logistic Regression.
- Published in:
- Toxicological Sciences, 2010, v. 118, n. 1, p. 251, doi. 10.1093/toxsci/kfq233
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- Publication type:
- Article
Incorporating Human Dosimetry and Exposure into High-Throughput In Vitro Toxicity Screening.
- Published in:
- Toxicological Sciences, 2010, v. 117, n. 2, p. 348, doi. 10.1093/toxsci/kfq220
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- Publication type:
- Article
tcpl: the ToxCast pipeline for high-throughput screening data.
- Published in:
- Bioinformatics, 2017, v. 33, n. 4, p. 618, doi. 10.1093/bioinformatics/btw680
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- Publication type:
- Article