We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
New Secodaphnane-Type Alkaloids with Cytotoxic Activities from Daphniphyllum angustifolium Hutch.
- Authors
Lu, Qing-Yun; Zhang, Jia-Hui; Li, Ying-Yao; Pu, Xue-Xue; Zhang, Cui-Shan; Liu, Shuai; Wan, Jia-Jia; Di, Ying-Tong; Hao, Xiao-Jiang
- Abstract
One new Daphniphyllum alkaloid, daphnioldhanol A (1), together with three known ones, were isolated from the stem part of Daphniphyllum angustifolium Hutch. Their structures were elucidated by spectroscopic methods and comparing with the literature data. Compound 2 is a new natural product, but known by synthesis as a racemate. Compound 1 exhibited week cytotoxic activity against Hela cell line with IC50 of 31.9 μM.
- Subjects
HELA cells; NATURAL products; CELL lines; ISOQUINOLINE alkaloids; NEW product development; ALKALOIDS
- Publication
Natural Products & Bioprospecting, 2021, Vol 11, Issue 4, p453
- ISSN
2192-2209
- Publication type
Article
- DOI
10.1007/s13659-021-00309-w