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- Title
Middle-term outcomes in renal transplant recipients with COVID-19: a national, multicenter, controlled study.
- Authors
Oto, Ozgur Akin; Ozturk, Savas; Arici, Mustafa; Velioğlu, Arzu; Dursun, Belda; Guller, Nurana; Şahin, İdris; Eser, Zeynep Ebru; Paydaş, Saime; Trabulus, Sinan; Koyuncu, Sümeyra; Uyar, Murathan; Ural, Zeynep; Sadioğlu, Rezzan Eren; Dheir, Hamad; Koç, Neriman Sıla; Özer, Hakan; Durak, Beyza Algül; Gül, Cuma Bülent; Kasapoğlu, Umut
- Abstract
Background In this study, we evaluated 3-month clinical outcomes of kidney transplant recipients (KTR) recovering from COVID-19 and compared them with a control group. Method The primary endpoint was death in the third month. Secondary endpoints were ongoing respiratory symptoms, need for home oxygen therapy, rehospitalization for any reason, lower respiratory tract infection, urinary tract infection, biopsy-proven acute rejection, venous/arterial thromboembolic event, cytomegalovirus (CMV) infection/disease and BK viruria/viremia at 3 months. Results A total of 944 KTR from 29 different centers were included in this study (523 patients in the COVID-19 group; 421 patients in the control group). The mean age was 46 ± 12 years (interquartile range 37–55) and 532 (56.4%) of them were male. Total number of deaths was 8 [7 (1.3%) in COVID-19 group, 1 (0.2%) in control group; P = 0.082]. The proportion of patients with ongoing respiratory symptoms [43 (8.2%) versus 4 (1.0%); P < 0.001] was statistically significantly higher in the COVID-19 group compared with the control group. There was no significant difference between the two groups in terms of other secondary endpoints. Conclusion The prevalence of ongoing respiratory symptoms increased in the first 3 months post-COVID in KTRs who have recovered from COVID-19, but mortality was not significantly different.
- Subjects
KIDNEY transplantation; URINARY tract infections; BK virus; COVID-19; TREATMENT effectiveness; RESPIRATORY infections
- Publication
Clinical Kidney Journal, 2022, Vol 15, Issue 5, p999
- ISSN
2048-8505
- Publication type
Article
- DOI
10.1093/ckj/sfac045