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- Title
Soluble tumor necrosis factor (TNF) receptor-1 induces apoptosis via reverse TNF signaling and autocrine transforming growth factor-β1.
- Authors
Waetzig, Georg H.; Rosenstiel, Philip; Arlt, Alexander; Till, Andreas; Bräutigam, Karen; Schäfer, Heiner; Rose-John, Stefan; Seegert, Dirk; Schreiber, Stefan
- Abstract
Presents a study that investigated whether soluble tumor necrosis factor-α has any signaling functions beyond its known role of neutralizing and buffering tumor necrosis factor-α in the circulation. Characterization of novel signaling pathways in primary monocytes and a monocytic model system; Principal findings; Conclusions and significance.
- Subjects
TUMOR necrosis factors; MONOCYTES; LEUCOCYTES; MACROPHAGES; APOPTOSIS
- Publication
FASEB Journal, 2005, Vol 19, Issue 1, p91
- ISSN
0892-6638
- Publication type
Article
- DOI
10.1096/fj.04-2073fje