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Welcome to the statistics and pharmacometrics themed issue.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 4, p. 273, doi. 10.1002/psp4.12625
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- Article
Impact of study design and statistical model in pharmacogenetic studies with gene‐treatment interaction.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 4, p. 340, doi. 10.1002/psp4.12624
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R and nlmixr as a gateway between statistics and pharmacometrics.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 4, p. 283, doi. 10.1002/psp4.12618
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Estimands—What they are and why they are important for pharmacometricians.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 4, p. 279, doi. 10.1002/psp4.12617
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Evaluation of bias in weighted residual calculations when handling below the limit of quantification data using Beal's M3 method.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 4, p. 275, doi. 10.1002/psp4.12616
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Conditional distribution modeling as an alternative method for covariates simulation: Comparison with joint multivariate normal and bootstrap techniques.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 4, p. 330, doi. 10.1002/psp4.12613
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- Article
Bench‐to‐bedside translation of chimeric antigen receptor (CAR) T cells using a multiscale systems pharmacokinetic‐pharmacodynamic model: A case study with anti‐BCMA CAR‐T.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 4, p. 362, doi. 10.1002/psp4.12598
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Issue Information.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 4, p. 269, doi. 10.1002/psp4.12525
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- Article
A novel method based on unbiased correlations tests for covariate selection in nonlinear mixed effects models: The COSSAC approach.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 4, p. 318, doi. 10.1002/psp4.12612
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Approaches to handling missing or "problematic" pharmacology data: Pharmacokinetics.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 4, p. 291, doi. 10.1002/psp4.12611
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Identification of high‐dimensional omics‐derived predictors for tumor growth dynamics using machine learning and pharmacometric modeling.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 4, p. 350, doi. 10.1002/psp4.12603
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- Article
Detecting placebo and drug effects on Parkinson's disease symptoms by longitudinal item‐score models.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 4, p. 309, doi. 10.1002/psp4.12601
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Network model‐based screen for FDA‐approved drugs affecting cardiac fibrosis.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 4, p. 377, doi. 10.1002/psp4.12599
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Opportunities and challenges for applying model‐informed drug development approaches to gene therapies.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 4, p. 286, doi. 10.1002/psp4.12597
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- Article