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- Title
Endoluminal MR imaging of porcine gastric structure in vivo.
- Authors
Yoshinaka, Hayato; Morita, Yoshinori; Matsuoka, Yuichiro; Obata, Daisuke; Fujiwara, Shoko; Chinzei, Ryo; Sugimoto, Maki; Sanuki, Tsuyoshi; Yoshida, Masaru; Inokuchi, Hideto; Kumamoto, Etsuko; Kuroda, Kagayaki; Azuma, Takeshi; Kutsumi, Hiromu
- Abstract
Recently, several new endoscopic instruments have been developed. However, even with the full use of current modalities, the safety of endoscopic surgery is not guaranteed. Information regarding factors such as fibrosis and the blood vessels under the mucosa is very important for avoiding procedure-related complications. The aim of this study was to define the detailed anatomy of the gastric wall structure in vivo using original endoluminal radiofrequency coils for safer endoscopic therapy. Swine were used as the subjects and controlled with general anesthesia. Anatomical images were obtained with T1-weighted fast spin echo (T1FSE) and T2-weighted fast spin echo (T2FSE). Dynamic magnetic resonance (MR) angiography was also obtained with three-dimensional T1-weighted fast spoiled gradient recalled acquisition in the steady state (3D-DMRA) following the injection of hyaluronic acid sodium into the submucosal layer. Porcine gastric wall structure was visualized, and four layers were discriminated in the T1FSE and T2FSE images. The vascular structure was clearly recognized in the submucosa on 3D-DMRA. Endoluminal MR imaging was able to visualize the porcine stomach with similar quality to endoscopic ultrasonography imaging. Additionally, it was possible to visualize the vascular structures in the submucosal layer. This is the first report to show that blood vessels under the gastric mucosa can be depicted in vivo.
- Subjects
ENDOSCOPY; ENDOSCOPIC surgery; FIBROSIS; ANGIOGRAPHY; HYALURONIC acid; ULTRASONIC imaging
- Publication
Journal of Gastroenterology, 2010, Vol 45, Issue 6, p600
- ISSN
0944-1174
- Publication type
Article
- DOI
10.1007/s00535-010-0201-0