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- Title
Muscle fiber type-specific myofibrillar Ca(2+) ATPase activity after spinal cord injury.
- Authors
Castro, Michael J.; Apple, David F.; Melton-Rogers, Sandee; Dudley, Gary A.; Castro, M J; Apple, D F Jr; Melton-Rogers, S; Dudley, G A
- Abstract
Biopsies of the vastus lateralis muscle were analyzed to determine if increased energy demand of contraction, as indirectly reflected by myofibrillar Ca(2+) adenosine triphosphate activity (qATPase), contributes to greater fatigue in affected muscle of spinal cord injured (SCI) patients. The qATPase activity showed a fiber-type effect, IIax + IIx > IIa > I. Average fiber qATPase and fiber specific qATPase activities were not different between SCI and able-bodied controls, nor did they change over time. We suggest greater fatigue in SCI subjects early after injury does not reflect increased energy demand of contraction.
- Publication
Muscle & Nerve, 2000, Vol 23, Issue 1, p119
- ISSN
0148-639X
- Publication type
journal article
- DOI
10.1002/(SICI)1097-4598(200001)23:1<119::AID-MUS17>3.0.CO;2-Z