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- Title
Desmoplastic fibroma of bone.
- Authors
Inwards, Carrie Y.; Krishnan Unni, K.; Beabout, John W.; Sim, Franklin H.; Inwards, C Y; Unni, K K; Beabout, J W; Sim, F H
- Abstract
Desmoplastic fibroma is a rare primary tumor of bone that histologically and biologically mimics the extra-abdominal desmoid tumor of soft tissue. This study reviews 27 cases of desmoplastic fibroma, consisting of 9 from the Mayo Clinic files and 18 from our consultation files. There was a male predominance, and 74% of the patients were in the first 3 decades of life. The most frequent sites of involvement were the metaphysis of long bones and the mandible. Radiographically, the tumors were lucent, expansile lesions with well-defined margins. Histologically, they contained slender spindle cells and various amounts of collagen fibers. En bloc resection is the treatment of choice because a high incidence of recurrence was noticed after lesional curettage.
- Subjects
BONE tumors; CANCER relapse; CELL nuclei; COLLAGEN; FIBROBLASTS; LONGITUDINAL method; PROGNOSIS; RADIOGRAPHY; CONNECTIVE tissue tumors
- Publication
Cancer (0008543X), 1991, Vol 68, Issue 9, p1978
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/1097-0142(19911101)68:9<1978::AID-CNCR2820680922>3.0.CO;2-H