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- Title
In Reference to Distinct Histopathology Characteristics in Empty Nose Syndrome.
- Authors
Salzano, Francesco Antonio; Vaira, Luigi Angelo; Maglitto, Fabio; Mesolella, Massimo; De Riu, Giacomo
- Abstract
Dear Editor: We have read with great attention to the recent article "Distinct Histopathology Characteristics in Empty Nose Syndrome".1 In particular, we have appreciated the efforts of Ching-Lung et al. to define the histopathological and molecular patterns for the identification of this controversial syndrome. First, in the cohort of 17 enrolled patients with Empty Nose Syndrome (ENS), there is a significant percentage of subjects (35%) affected by allergic rhinitis that could be a confounding factor on the results. In fact, if this assumption were true, it is not clear how submucosal reconstruction over the lateral wall of the nasal cavity in these patients could resolve the nasal obstructive symptoms in the presence of an underexpression of these receptors.
- Subjects
HISTOPATHOLOGY; TRP channels; NOSE; NASAL polyps
- Publication
Laryngoscope, 2021, Vol 131, Issue 4, pE1038
- ISSN
0023-852X
- Publication type
Article
- DOI
10.1002/lary.29181