We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
ASSOCIATION BETWEEN NEUTROPHIL TO LYMPHOCYTE RATIO AND PLATELET TO LYMPHOCYTE RATIO WITH DIABETIC RETINOPATHY AMONG TYPE-II DIABETIC PATIENT AT A TERTIARY CENTER.
- Authors
Kumawat, Balkishan; Jat, Ram Kishan; Bansal, Dharam Prakash; Rijhwani, Puneet; Choudhary, Shrikant; Sanadhya, Abhishek
- Abstract
Introduction: Diabetic retinopathy (DR) is important microvascular complication of diabetes mellitus (DM) and one of the main causes of blindness worldwide, but an effective screening is challenging due to limited available retina specialists. Developing new biomarkers could help clinical decision in prioritizing ophthalmological consultation in patients at risk of developing severe DR. Aim: To evaluate the association between Diabetic retinopathy and the Neutrophil Lymphocyte ratio, and the Platelet Lymphocyte Ratio Methods: Hospital based Case Control study on 360 diabetic patients . 180 patients were taken as cases who have DM with retinopathy and 180 patients were taken as controls who have DM without retinopathy with age between 18 to 65 years at Mahatma Gandhi Hospital, Jaipur from September 2022 to August 2023. Results: Compared with control patients, NLR and PLR levels are signifcantly higher among cases (NLR: 2.29 ±1.21 in controls versus 2.91 ±1.98 in cases and p<0.001; PLR: 108.13 ±75.21 137.89 ±26.98 and p<0.001). Conclusion: High NLR and PLR increase the risk of Diabetic Retinopathy and these insights emphasize the importance of comprehensive diabetic management strategies that not only target blood glucose levels but also monitor and manage inflammatory markers to improve patient outcomes and reduce the burden of diabetic retinopathy.
- Subjects
PLATELET lymphocyte ratio; NEUTROPHIL lymphocyte ratio; TYPE 2 diabetes; DIABETIC retinopathy; DIABETES complications; PEOPLE with diabetes
- Publication
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research), 2024, Vol 15, Issue 7, p2301
- ISSN
0975-3583
- Publication type
Article