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- Title
Relationship of Electrocardiographic Dynamicity to Ischemic Burden Using Myocardial Perfusion Imaging in Patients without Previous Myocardial Infarction.
- Authors
Ali Hamed, Amr Hamed; Badran, Hala Mahfouz; Ahmed, Naglaa Fahiem; Soliman, Ahmed Elsayed
- Abstract
Objectives: To examine Relationship of Electrocardiographic Dynamicity to Ischemic Burden Using Myocardial Perfusion Imaging in Patients without Previous Myocardial Infarction. Background: Myocardial perfusion Imaging (MPI) provides powerful diagnostic and prognostic information in the management of patients with known or suspected coronary artery disease (CAD). The purpose of this study was to study the relationship of electrocardiographic dynamicity to ischemic burden using MPI in patients without previous myocardial infarction. Method: our study was a prospective observational which was carried out on 175 patients referred for diagnosis or risk stratification for coronary artery disease, patients were subjected to a history checkup and full clinical examination, a standard 12-lead electrocardiograms at rest & subjects underwent technetium(Tc)-99m sestamibi rest-stress gated SPECT MPI. Results: There was a fair agreement between exercise treadmill induced electrocardiogram (ECG) ischemic changes in anterior leads and myocardial perfusion defects in MPI at stress of the studied patients, and there was a moderate agreement between, exercise treadmill induced ECG ischemic changes in inferior leads and negative stress ECG, and myocardial perfusion defects in MPI at stress of the studied patients. In Age <50y with one or no risk factors, there was a fair agreement between MPI and stress ECG. In Age >50y with one or more risk factors, there was a moderate agreement between MPI and stress ECG. Stress ECG can diagnose CAD and ischemic heart disease as MPI at stress with82.9% sensitivity, 69.0% specificity. Conclusions: Exercise treadmill induced ECG ischemic changes can diagnose the ischemic burden with less accuracy than the MPI at stress regarding the evidence of ischemia while it was irrelevant with myocardial perfusion defects in MPI at stress regarding the distribution of ischemic changes.
- Subjects
MYOCARDIAL perfusion imaging; CORONARY disease; MYOCARDIAL ischemia; CORONARY artery disease; TREADMILLS; MYOCARDIAL infarction
- Publication
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research), 2024, Vol 15, Issue 7, p1791
- ISSN
0975-3583
- Publication type
Article