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- Title
Severe pulmonary haemorrhage syndrome in leptospirosis in a returning traveller.
- Authors
Schönfeld, Andreas; Jensen, B.; Orth, H. M.; Tappe, D.; Feldt, T.; Häussinger, D.
- Abstract
Clinical presentation of leptospirosis ranges from asymptomatic infection to fulminant, life-threatening disease. Pulmonary involvement in terms of severe pulmonary haemorrhage syndrome (SPHS) has recently become a more frequently reported facet of leptospirosis and correlates with high mortality rates. It has not yet been described in returning German travellers. We present a case of a healthy young man developing massive pulmonary haemorrhage and severe ARDS requiring mechanical ventilation and high-dose catecholamines after travelling to Indonesia. Leptospirosis was verified by blood PCR as well as serology and treated with high-dose, intravenous penicillin. Outcome was favourable, the patient recovered completely. Leptospirosis and SPHS should be taken into account as an emerging infectious disease in patients with fever and lung involvement.
- Subjects
INDONESIA; RESPIRATORY distress syndrome; HEMORRHAGE risk factors; CATECHOLAMINES; ARTIFICIAL respiration; INTRAVENOUS therapy; LEPTOSPIROSIS; LUNGS; PENICILLIN; POLYMERASE chain reaction; TRAVEL; TREATMENT effectiveness; SEVERITY of illness index; DISEASE complications; THERAPEUTICS; DISEASE risk factors
- Publication
Infection, 2019, Vol 47, Issue 1, p125
- ISSN
0300-8126
- Publication type
Article
- DOI
10.1007/s15010-018-1220-7