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- Title
Chiari 1 malformation and raised intracranial pressure.
- Authors
Piper, Rory J.; Magdum, Shailendra A.
- Abstract
Background: The pathophysiology of Chiari 1 malformation (CM1) is inextricably related to intracranial pressure (ICP). The characteristic cerebellar tonsil herniation at the foramen magnum may either cause raised ICP by disturbing CSF flow (as observed in idiopathic CM1) or may itself be the effect of raised ICP (as observed in acquired CM1). Distinguishing between these two phenomena, therefore, is of paramount importance in successfully alleviating the symptoms of the condition and preventing serious complications. Objectives: In this article, we discuss the pathophysiology of raised ICP in CM1 and review the current evidence for its investigation and treatment. We also share our own clinical experience which investigates the utility of ICP monitoring in a series of 26 children with CM1.
- Subjects
ARNOLD-Chiari deformity; INTRACRANIAL pressure; PATHOLOGICAL physiology; HERNIA; TONSILS
- Publication
Child's Nervous System, 2019, Vol 35, Issue 10, p1719
- ISSN
0256-7040
- Publication type
Article
- DOI
10.1007/s00381-019-04232-x