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- Title
Sister Mary Joseph's nodule associated with rare endometrial squamous cell carcinoma.
- Authors
Rahman, Mohammed; Nakayama, Kentaro; Rahman, Munmun; Nakayama, Naomi; Ishikawa, Masako; Katagiri, Atsuko; Katagiri, Hiroshi; Ishibashi, Tomoka; Iida, Kouji; Miyazaki, Kohji
- Abstract
Background: Umbilical metastasis (Sister Mary Joseph's nodule) is a rare physical sign seen only in 1-3 % of patients with an intra-abdominal and/or pelvic malignancy. Here, we present a case of Sister Mary Joseph's (SMJN) nodule originating from a primary squamous cell carcinoma of the endometrium, a rare histological subtype. Case history: SMJN was detected in a 30-year-old woman after a preoperative CT scan for a suspected umbilical hernia. Subsequent laparotomy and histopathological examination confirmed endometrial squamous cell carcinoma metastasizing to the umbilical region. Conclusion: The SMJN may be the first presenting sign of an intra-abdominal and/or pelvic malignancy and may co-exist with an umbilical hernia. Therefore, malignancy should be considered one of the differentials of an umbilical mass.
- Subjects
UMBILICAL hernia; ENDOMETRIAL cancer; SQUAMOUS cell carcinoma; CANCER tomography; CANCER histopathology; ABDOMINAL surgery; PELVIS cancer
- Publication
Archives of Gynecology & Obstetrics, 2012, Vol 286, Issue 3, p711
- ISSN
0932-0067
- Publication type
Article
- DOI
10.1007/s00404-012-2356-9