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- Title
Chronic itch in African Americans: an unmet need.
- Authors
Ingrasci, Giuseppe; El-Kashlan, Nour; Alexis, Andrew; Yosipovitch, Gil
- Abstract
Chronic pruritus carries a significant burden of disease and is associated with a negative impact on quality of life. African Americans are disproportionately burdened by chronic pruritic disorders, including but not limited to atopic dermatitis, prurigo nodularis, inflammatory scalp dermatoses, pathologic scarring, and HIV-related dermatoses. Racial differences in skin structure and function may contribute to the pathogenesis of itch in African Americans. Itch perception and response to treatment in African Americans remain understudied and not well understood. As such, there is a large unmet need with regard to the knowledge and management of pruritus in African Americans. This review highlights notable differences in the epidemiology, pathophysiology, genetic predisposition, clinical presentation, and response to treatment for select pruritic skin conditions. By addressing itch as an unmet need in African Americans, we hope to improve patient outcomes and lessen disparities in dermatologic care.
- Subjects
ITCHING; AFRICAN Americans; ATOPIC dermatitis; SYMPTOMS; PRURIGO; SEBORRHEIC dermatitis
- Publication
Archives of Dermatological Research, 2022, Vol 314, Issue 5, p405
- ISSN
0340-3696
- Publication type
Article
- DOI
10.1007/s00403-021-02255-6