We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Monocyte/mesangial cell interactions in high‐glucose co‐cultures.
- Authors
Menè, Paolo; Caenazzo, Cristina; Pugliese, Francesco; Cinotti, Giulio A.; D'Angelo, Angela; Garbisa, Spiridione; Gambaro, Giovanni
- Abstract
Background. Monocytes bind to human mesangial cells (HMC) in a co‐culture model of leukocyte/ glomerular cell interactions. Since monocytic infiltration has been demonstrated in the early stages of diabetic glomerulopathy, we examined whether co‐culture with myelomonocytes of the U937 cell line in media mimicking the diabetic microenvironment modulated phenotype, growth, and extracellular matrix production patterns of HMC.
- Publication
Nephrology Dialysis Transplantation, 2001, Vol 16, Issue 5, p913
- ISSN
0931-0509
- Publication type
Article
- DOI
10.1093/ndt/16.5.913