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- Title
B lymphopenia in uraemia is related to an accelerated in vitro apoptosis and dysregulation of Bcl-2.
- Authors
Fernández-Fresnedo, Gema; Ramos, María Angeles; González-Pardo, Maria Consuelo; de Francisco, Angel Luis Martín; López-Hoyos, Marcos; Arias, Manuel
- Abstract
Background. Lymphopenia has been described in patients with chronic renal failure (CRF). It is postulated that the decline in lymphocytes is due to accelerated apoptosis. We investigated whether dysregulation of programmed cell death plays a role in the immunodeficiency described in CRF.
- Publication
Nephrology Dialysis Transplantation, 2000, Vol 15, Issue 4, p502
- ISSN
0931-0509
- Publication type
Article