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- Title
Relationship between antibiotic consumption and frequency of antibiotic resistance of four pathogens—a seven-year survey.
- Authors
Mouton, R. P.; Glerum, J. H.; van Loenen, A. C.
- Abstract
The resistance rates of , spp., and spp. for four antibiotics were established yearly for a period of 7 years. Strains were grouped according to their origin. An attempt was made to correlate the resistance rates of hospital isolates with data on antibiotic consumption. A rising benzylpenicillin resistance rate of staphylococci did not correlate with penicillin consumption, but could be explained by an increase in the consumption of penicillin and ampicillin together. The kanamycin resistance rates of enterobacteria rose along with an increase in kanamycin usage. For spp. and , the reverse was found with regard to tetracycline. In spite of an increasing ampicillin consumption the ampicillin resistance rates of and spp. decreased. Some possible explanations for the results are discussed.
- Publication
Journal of Antimicrobial Chemotherapy (JAC), 1976, Vol 2, Issue 1, p9
- ISSN
0305-7453
- Publication type
Article