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- Title
COMPARISON OF METHYL VIOLET INTERACTION WITH BOVINE SERUM ALBUMIN AND HUMAN SERUM ALBUMIN BY UV-DENATURATION METHOD.
- Authors
SHAHINYAN, M. A.; MIKAELYAN, M. S.; PARSADANYAN, M. A.; ANTONYAN, A. P.
- Abstract
In the present work the interaction of methyl violet (MV) with human serum albumin (HSA) and bovine serum albumin (BSA) has been studied by the UVdenaturation method and the obtained data were compared. The denaturation parameters - denaturation temperature and denaturation interval width, were determined. It was shown that MV, binding to serum albumins, stabilizes their structure. At the same time, the stabilization degree is different. It was also shown that BSA is stabilized more, than HSA, while binding to MV.
- Subjects
GENTIAN violet; SERUM albumin; DENATURATION of proteins; X-ray crystallography; TERTIARY structure
- Publication
Proceedings of the YSU B: Chemical & Biological Sciences / Gitakan Teghekagir. K'imia, Kensabanut'yun, 2022, Vol 56, Issue 2, p136
- ISSN
1829-1767
- Publication type
Article
- DOI
10.46991/PYSU:B/2022.56.2.136