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- Title
Clinical Remission of Cutaneous Squamous Cell Carcinoma of the Auricle with Cetuximab and Nivolumab.
- Authors
Chen, Alessandra; Ali, Nabilah; Boasberg, Peter; Ho, Allen S.
- Abstract
Cutaneous squamous cell carcinomas (SCC) affecting the regions of the head and neck can be challenging to resect surgically and refractory to chemotherapy or radiation therapy. Consequently; the treatment of squamous cell carcinomas of the skin is a focus of current research. One such advancement is immunotherapy. Herein we describe clinical remission of invasive, poorly differentiated squamous cell carcinoma of the pre-auricular region with external auditory canal involvement using cetuximab, an epidermal growth factor receptor (EGFR) antibody; and nivolumab, a programmed death receptor-1 (PD-1) antibody. Such durable and comprehensive disease resolution demonstrates the therapeutic potential of cetuximab and nivolumab in surgically challenging, treatment-resistant cutaneous squamous cell carcinoma.
- Subjects
SQUAMOUS cell carcinoma; MEDICAL radiography; DIAGNOSTIC imaging; CANCER chemotherapy; CANCER treatment
- Publication
Journal of Clinical Medicine, 2018, Vol 7, Issue 1, p10
- ISSN
2077-0383
- Publication type
Article
- DOI
10.3390/jcm7010010